Chrome - Disable cache for localhost only?
Solution 1
You can certainly prevent all your file from hitting the cache, but this is an all-or-nothing setting. You can't decide which files get cleared from the cache and which files stay in the cache.
During development, since you are using Chrome, I'd recommend to enable the setting for "Disable cache (while DevTools is open)":
If you are like me, cache will be disabled every time you have the DevTools panel opened.
Another thing you can do is to instruct your server to bypass cache altogether for all your resources. Since jQuery is coming from a CDN, this no-cache setting won't apply for it. To disable cache for resources you can include the following response header:
Cache-Control:no-cache, no-store
Solution 2
If you are using Apache you can disable cache on your server (localhost) by placing .htaccess file into your htdocs directory (or directory which you want to disable the cache for) with following content:
FileETag None
<ifModule mod_headers.c>
Header unset ETag
Header set Cache-Control "max-age=0, no-cache, no-store, must-revalidate"
Header set Pragma "no-cache"
Header set Expires "Wed, 11 Jan 1984 05:00:00 GMT"
</ifModule>
Solution 3
Press Ctrl+Shift+i to open developer tools, then go to network
tab, and click on Disable cache

Comments
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songyy 6 months
I'm using localhost for development; and I'm directly including jquery from CDN.
It seems that pressing the "Ctrl + R" would force the page to reload, including re-downloading the jquery from CDN.
I want to ask if it's possible that.. when I refresh, I keep the cache of the jquery from CDN, but clear the cache of my localhost?
NOTE: I know that one thing I can do is to host jquery file locally; I'm just asking to see if there's a way to bypass that.
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Oussama Bouthouri about 5 yearsFor the current version of chrome "61", this feature moved to the developer tool. To activate it you have to go to: More Tools > Developer tools > Network "tab" then click on Disable cache. Note that this work only when the Developer tool is open.